Topical treatments such as moisturizer application and the soaking of cracked paws can help to soothe soreness while the underlying problem is addressed. Since I can't see how severely Storme is affected, it is difficult to say how he may respond to therapy, but if he responds well, he may live a normal life. Your vet may be able to diagnosis feline plasma cell pododermatitis by the initial physical exam and the classic physical symptoms. Who is affected by feline plasma cell pododermatitis?Feline plasma cell pododermatitis can affect any age, gender, or breed of cat. 1st ed. In this case the lesions affected all paws and all digits, including the dewclaws. Home Cat 5 Natural Treatments for Plasma Cell Pododermatitis (Pillow Foot) In Cats. Feline plasma cell pododermatitis is a rare dermatological condition exclusively described in cats. and . The cause is unknown, although the disease may be immune-mediated based on the frequent finding of hypergammaglobulin Aemia, plasma cell infiltration and response to glucocorticoids. Thank you Ask Ariel for giving our sweet Toby a better life." Cat owner may need to give special care and attention to cat in recovery period and keep it healthy. Diagnosis of feline plasma cell pododermatitisIf you discover that your cat has soft, swollen, tender, scaly footpads, be sure to bring him to your veterinarian for an examination. Now after three months, his little paw looks almost back to normal with NO limp. We started with many speculations since Toby is such a sensitive, one of a kind cat. - Dawn, Pennsylvania, "Just am so happy to tell you how well Boo is doing after 3 days of treatment (Immune Support Kit). In: Muller and Kirk's Small Animal Dermatology. In very mild cases, the cat may not be experiencing any discomfort. As the weeks went on, it was clear that he was getting worse and was suffering from Pillow Foot. Ask Ariel's time-tested home remedies for pillow foot in cats have been used successfully since 2005 and are recommended by veterinarians nationwide. Brachial Plexus Avulsion in Dogs and Cats. A cat with feline lung-digit syndrome; paronychia, hemorrhage and fixed exsheathment of the nail are evident. Has your cat been diagnosed with feline plasma cell pododermatitis? Soak the cats paws for 30 seconds and allow the paws to air dry. Figure 5. Domestic breed cats are over-represented, sex predilection has not been confirmed, but two recent reviews suggest that females may be marginally more prone to the condition 1314. If so, there is so much you can do to give your cat fast relief from a cat paw pad infection. By Franais 2023 - Improve International, Alexandra House, Whittingham Drive, Wroughton, Swindon, Wiltshire SN4 0QJ, England. Published 09/09/2021. VIN Public Log out. Oral administration of prednisone or glucocorticoid on a daily basis can be effective. Who is affected by feline plasma cell pododermatitis? Snake bites may need antivenom injections. Cats will often present to first opinion clinics with a variety of foot lesions; Ronnie Kaufmann discusses the main differentials, diagnostics and treatment options. Feline Plasma Cell Pododermatitis Feline plasma cell pododermatitis (FPP) most commonly causes swelling of the metacarpal pads, metatarsal pads, or digital pads. The exact etiology and pathogenesis are not fully elucidated, although many studies have looked at possible triggers. The excessive grooming on the affected area can cause further inflammation even ulceration. Disclaimer | Although the exact etiopathogenesis of FEGC is unclear, most evidence points to an underlying hypersensitivity to insects (mostly fleas), environmental allergens or foods. The cat may eventually become quite lame if the paws become too damaged. He also seems much happier and more content now. Guaguere E, Prelaud P, DegorceRubiales F, et al. The main differential diagnosis for PCP is eosinophilic granuloma, although the latter frequently has concurrent skin lesions, rarely affects multiple paws, and tends to affect the interdigital spaces rather than only the paw-pads2 3. I just wanted to let you know that you are a blessing and I am so thankful." Metastatic pulmonary carcinomas in cats (feline lung-digit syndrome): further variations on a theme. Figure 1. Pododermatitis is often associated with renal amyloidosis (a kidney disease) or plasma cell stomatitis (a disease of the mouth). pillow that looks like your cat Ronnie Kaufmann, Figure 3. Special attention may be needed to keep the affected feet clean throughout the healing process. Vet Dermatol 2004;15:27. Bloat - The Mother of All Emergencies. A definitive diagnosis relies on histopathology, and whilst therapy commonly involves immunomodulation, it is different for every disease, as is the prognosis. It is painful, but does not present a life-threatening emergency. 2021 IDEXX Laboratories, Inc. All rights reserved. The pulp of this famous herbal plant can reduce pain and inflammation, and also help to promote healing process and tissue repair that is needed for treatment for pillow foot. Most cats require long-term treatment due to the high frequency of relapse which can be due to drug tapering or discontinuation, but can also occur in well controlled cases 131415161718. Supportive care through immune modulating supplements can help to balance the immune system and prevent flare-ups and inflammation. Another solution we can make with unpasteurized apple cider vinegar is to add it with warm water, lemon juice and peppermint oil. These signs are followed by hyperkeratosis and ulcerations that may bleed. 2. Cats that show a poor response to doxycycline can be given a steroid such as prednisolone. A minority of affected cats also have plasma cell stomatitis, immune-mediated glomerulonephritis, or renal amyloidosis; may have concurrent indolent ulcers or eosinophilic granulomas. Affected pads are typically: The pads might then become painful and cause your cat to limp. 7th ed. Feline pemphigus foliaceus: original case series and a comprehensive literature review. Blastomycosis is a Systemic Fungal infection Affecting Dogs and Cats. $122 for a bottle that will only last 2 months. Hello. Some mild cases of feline plasma cell pododermatitis regress spontaneously without treatment. Log in, Worldwide medical and scientific journal for animal health professionals, Royal Canin, Health Nutrition for Cats and Dogs. Pemphigus foliaceus in feline patients. These are all inflammatory conditions that can weaken the bodys natural immune response. The veterinarian will have to differentiate pillow foot from other issues that involve the foot pads, such as insect bites and cancerous or benign tumors. In cases with secondary infections, more specific antibiotics and antifungal medications may be necessary. For a cat, that's 1/8 to 1/4 tsp. I started researching Pillow Foot and came across Ask Ariel's website. As with PCP, the prognosis for EG is variable, and spontaneous resolution is possible. Plasma cell pododermatitis is a rare disease of cats, with a probably immune origin. In the absence of complications such as glomerulonephritis or renal amyloidosis, the prognosis is good. This ulceration may bleed and split open which is harmful if it is infected. The veterinarian will then perform a complete physical examination of the cat. An affected paw pad will feel mushy and balloon out from swelling. David was hospital director at RSPCA Harmsworth for 25 years and now writes and lectures internationally, mainly in dermatology. Along with being a writer and media personality, she is also a founding member of IDEXXs Pet Health Network team. Pillow foot usually may heal on its own, although there are also more serious cases such as involvement of other underlying health issues. Epsom salt or magnesium sulfate is the first of 5 natural treatments for plasma cell pododermatitis (pillow foot) in cats as it can reduce swelling and inflammation. Hyperkeratosis and variable pigmentation of the footpads is common, and pruritus can be intense. Pillow Foot in Cats (Plasma Cell Pododermatitis in Cats) is a rare disease of the footpads of cats. When this is present without other dermatological lesions the suspicion should be very high, and fine-needle aspiration (FNA) from a swollen pad showing plasma cells2 36(Figure 4) will support the notion. PCP often occurs concurrently with feline immunodeficiency virus (FIV), so a thorough diagnostic approach is advised for any cat showing symptoms of PCP. It is better to use the warm water. I am most certain that the Power Probiotic is what cleared up the pillow paw and continues to help him out with his digestion and immune system today as I still put some in his food daily. The digital pads may also be affected, but usually to a lesser degree. When a single pad is affected, neoplasia or a foreign body should be considered 3. Eight cases of feline plasma cell pododermatitis, collected over a 3-year period, were studied using histological (haematoxylin and eosin), histochemical (methyl green-pyronin) and immunohistochemical (antibody against lambda light chains of immunoglobulins) techniques. What causes my cat vomit so much? Ronnie Kaufmann, Figure 7. Beside of medicines, there are also some natural treatments for plasma cell pododermatitis (pillow foot) in cats. Secondary bacterial infection is not uncommon 23 45 67 8. Conventional veterinary plasma cell pododermatitis cat treatment typically includes antibiotics to clear infection and steroids to calm the inflammation. Feline Plasma Cell Pododermatitis: My Cat Has a Sore Paw, Your veterinarian may recommend screening your cat for FIV, Your veterinarian may suggest a fine needle aspirate or biopsy of the affected pads. Right: Plasma cell pododermatitis. A tentative diagnosis can be made based on typical clinical signs, as the hallmark of PCP is soft swelling of the central pads, with or without ulceration, and usually in more than one foot. Remember that natural and home care treatment can help but its the best to follow and have the professional treatment. What are plasma cells? It probably falls into the category of other lymphoproliferative disorders of cats. . Pododermatitis is the name given to the clinical presentation of an inflammation affecting the paws, although it can involve the skin of the paws, the interdigital spaces and/or the nail folds (paronychia). Plasma cell pododermatitis, also known as pillow foot, is a condition of severe inflammation on cats paws. The metastatic spread to the digits is thought to be due to the angioinvasive properties of these lesions and subsequent hematological spread. {{ getUser.first_name }} Cutaneous lymphoma in the cat is a rare but life-threatening neoplasm that warrants inclusion in the differential diagnosis list of many dermatology cases. Philadelphia, WB Saunders, 2013;695-723. These may provide temporary relief but over time with continued steroid use, will lose their effectiveness. The clinical presentation is very variable, as lesions can occur anywhere on the body, including the oral cavity. Cain CL, Mauldin EA. The differential diagnosis will depend on the number of feet affected, and the aforementioned causes of pododermatitis should be considered. I think I am happy that is the first round. Regards Dr Callum Turner DVM. How long can my cat live with this condition? He has been taking. That's when I found Ask Ariel! J Feline Med Surg open rep 2017;1-8. van der Limde-Sipman JS, van den Ingh TS. Contact Us | Lameness and pain are common if there are severe lesions affecting the paws. She is more energetic, comfortable, walking easily and most important her front left Pillow Paw is already healing. More advanced or painful lesions are commonly treated with doxycycline or steroids. We have been unable to get him to the vet's office because of COVID, and most recently because they are only seeing patients in the parking lot! Pododermatitis means "inflammation involving the skin on the foot." In this case, the inflammation is due to infiltration of the pad with plasma cells, which are a type of cell of the immune system. We were nervous to start the. Many cats with pillow foot will have multiple autoimmune conditions, such as IBD and stomatitis. Search resources and find a vet based on your pet's conditions. After starting him on the Power Probiotic, he has grown all his hair back, bathes more like a normal cat, instead of nervously & has even gained a few pounds. WOW!!! To confirm pillow paw, your veterinarian may need to run blood tests. Cheyletiellosis is a skin disease caused by infestation with Cheyletiella mites. If your cat has undergone surgery, you will need to follow all at-home care instructions provided by the surgeon. The main symptoms associated with PCP are: Swollen, puffy paw pads White lines on the paw pads Loss of pigment on the paw pads. Vet Rec 2003;152:564-566. An Elizabethan collar is often used when a cat is itchy, but they can also be detrimental to an animals wellbeing. These may provide temporary relief but over time with continued steroid use, will lose their effectiveness. Diet can play an important role in supporting your cats immune system. After the successful eradication of cats, pigs, and feral goats from the Lord Howe Island group, ship rats and mice were then targeted. Our cat was slightly reluctant at first, but quickly adjusted and we fed him this mixture to half a can of high protein no grain orgarnic wet food a day. My cat's biopsy just came back- lympho plasma cell pododermatitis. Pododermatitis is a descriptive term, not a final diagnosis, and can involve the skin of the paws, the interdigital spaces and/or the nail folds. Surgery may also be beneficial in severe cases. Ruth has more than 15 years of experience in the veterinary industry as a companion animal veterinarian in private practice. In order to understand what treatment works for pillow foot (plasma cell pododermatitis) you have to understand what this disease actually is. The condition may also come with more serious disease. Multiple foot pads particularly the central metacarpal or metatarsal. The treatment of choice for pododermatitis is doxycycline. The treatment should take 10 weeks to restore the normal appearance of the pads when administered a dose of 10 mg/kg per day. 2023 Animal Lova | Biopsy also confirms the diagnosis although it is rarely necessary. Lesions on the footpads are typically crusted and ulcerated (Figure 5). J Jpn Vet Cancer Soc 2010;1(1):8-13. Tissue eosinophilia, albeit supportive, is not diagnostic in itself for EG, and histologic evaluation is required to establish a diagnosis9 1011 . J Feline Med Surg 2012;14:471-481. Antibodies then attack healthy paws and cause swelling and pain to develop. Cat with pillow foot can have difficulty to walk because of the inflamed paw pads and pain. Vet Clin Small Anim 2019;49:95-104. The clinical picture and physical examination are very characteristic and the diagnosis is straightforward in most cases. With this dose, a complete cure can be expected in a third of cases and a clear improvement in about 80% of animals. Recurrence is very likely unless the primary cause is detected & treated. Suggested Articles Feline Skin Diseases The Challenge of Skin Disorders Flea Allergy Food Allergies A variety of ominous skin eruptions that can appear just about anywhere on a cat's body may signal the emergence of a troublesome condition referred to broadly as eosinophilic granuloma complex (EGC). Bizikova P. Autoimmune Diseases. Yeast. Differential diagnoses for EG footpad lesions include neoplasia (squamous cell carcinoma and mast cell tumor), infectious granuloma (bacterial folliculitis and furunculosis, mycobacteria, dermatophytes or deep fungal infection), abscessation, feline cowpox, foreign body reaction and sterile granulomatous disease910 11. Plasmas cell pododermatitis is an uncommon immune-mediated disease affecting the paw pads of cats. Pay attention to cleaning product we used around the house as it can be bad for cats paws. Typical signs include lameness, digital swelling, purulent nail bed discharge and fixed exsheathment of nails (Figure 9). He was found as a kitten injured and on the center stripe of a lonely two lane blacktop. Cats prescribed cyclosporine should be FIV and FeLV negative and should not be allowed to hunt or eat raw meat, due to the risk of developing fatal toxoplasmosis. J Feline Med Surg 2012;15(4):307-316. Although many cases of PCP do not have symptoms beyond swelling and sores on the affected paw pads, some cats may experience the following: Bleeding Pain Lameness Appetite loss Lymph node enlargement (lymphadenopathy). Sometimes higher doses (up to 4 mg/kg) may be required, and some cases will respond better to dexamethasone at 0.1-0.2 mg/kg (tapering to a maintenance dose of 0.05-0.1 mg/kg q72H), or triamcinolone 0.2-0.3 mg/kg daily. Stress-free CPD tracking and certification, youll wonder how you coped without it. Diseases affecting the pads include, though are not limited to, eosinophilic granuloma, pemphigus foliaceous, mosquito bite hypersensitivity, metastatic adenocarcinoma (so called "lung-digit syndrome") and plasma cell pododermatitis. Moe L, Lium B. J Small Anim Pract 38:498-505, 1997. Home remedies can be inexpensive, quick, and effective, despite the low cost of natural treatments. The cats paw pad surface may become purplish or have white striations and it can crack or ulcerate. This leads to swelling, loss of pigment, and open sores. By A more recent study looking at biopsies from 85 amputated feline digits identified a neoplastic disease in the majority (63) of cases, with 95.2% of them being malignant 24. What is plasma cell Pododermatitis in cats? Some cases of PCP may go away on their own without treatment. Miscellaneous skin diseases. Feline Plasma Cell Pododermatitis: My Cat Has a Sore Paw Good luck!! To learn more about how to help your pet with an autoimmune disease, "This is Eddie showing off his lovely paw. Feline Dermatology. Symptoms of feline plasma cell pododermatitisPododermatitis can affect any footpad, but most commonly it involves the large or central pad of the front or back feet (called the metacarpal or metatarsal pads). Cats should be kept indoors during active mosquito hours and/or wear a protective anti-parasitic collar 19. Autoimmune conditions like pillow foot are progressive, and without a holistic, integrative approach can lead to the development of other inflammatory autoimmune conditions. Bruising or purplish coloring on the foot pad, Feline Immunodeficiency virus (over 50 percent of cats with pillow foot are FIV positive). It is a pustular, erosive and crusting dermatosis involving the face, ears and feet. Obvious problems such as overgrown nails will be treated by trimming the nails. Update your browser to view this website correctly. Feline eosinophilic granuloma (EG) affecting the paws is a manifestation of one of the three common presentations of feline eosinophilic granuloma complex (FEGC)9 1011. WOW!!! There is still no exact treatment for pillow foot since the cause is still unknown. There has been success in treating immune system reactions which may be causing the footpad inflammation. After just one week, we were able to notice a marked improvement in his mobility. The large number of plasma cells present in the lesions suggests an immunological basis for the condition and suggests a seasonal occurrence of the condition. Being in a shelter prior, we thought a quality diet and nice quiet home would remedy this. Multiple affected paws, especially when accompanied by paronychia, could suggest an infectious etiology. Go to vet to check up the cats health regularly and if there is anything wrong with the cat. Secondary bacterial and fungal infections are common complications of PCP. After that dont rinse the paws to let the oatmeal properties to work. It can also improve circulation, have soothing effect, relieve the pain from swelling, and draw toxin out from body. A large proportion of these cases are also suffering with allergy, but the secondary yeast infection can be contributing as much as 90% of the inflammation and pruritus. Both males and females are susceptible to pododermatitis. Owners should be aware of this latter possibility from the time of diagnosis, and discussion of different treatment protocols and side effects is warranted. Attempting surgical amputation should be carefully considered, given the poor prognosis20 2122. PCP is not contagious to humans or to other animals. Treatment of PCP is directed at relieving pain and swelling as well as eliminating any secondary infections. Ronnie Kaufmann, Also available in Importantly, disease control is defined as cessation of active lesions and healing of original lesions and not necessarily complete disappearance of all signs 14. Eosinophilia may be present, although this is not a diagnostic feature9 1011. Dont rinse the paws after the footbaths since the healing properties of the substances needed to remain on the cats paws to give the best effect. Bladder Stones (Struvite) in Dogs. "Plasma Cell Pododermatitis" literally means foot inflammation involving infiltration by "plasma cells." Plasma cells are activated lymphocytes in full maturity, enthusiastically producing antibodies in response to some kind of inflammatory process, usually but not necessarily infection. Tapering the dose (20-25% reduction every 2-4 weeks) is recommended once the disease is inactive for at least 2 weeks and most original skin lesions have healed14151718. Ulceration of the central pad as typically seen in plasma cell pododermatitis. A definitive diagnosis relies on histopathology, and although therapy commonly involves immunomodulation, it is different for every disease, as is the prognosis. Pressanti C, Cadiergues MC. - Sue, Pennsylvania, Natural Treatments For Pillow Paw In Cats. Term of Use |, 5 Natural Treatments for Plasma Cell Pododermatitis (Pillow Foot) In Cats, How to Treat Cat Scratch Fever with Home Remedies, 3 Simple Home Remedies to Treat Cat Claw Fungus, 8 Popular Animals in East African Savanna, Most Popular Animals in Tropical Grassland, 6 Amazing Animals You can Only Find in the Thar Desert. It also has slightly anesthetic properties from peppermint oil. Search resources and find a vet based on your pet's symptoms. Typically, a cat will appear to be lame on the affected paws. Protect yourself and your pet. Typical histopathological findings consist of crusting which frequently spans numerous hair follicles, sub-corneal or intragranular pustules, numerous acantholytic keratinocytes, and a predominantly neutrophilic dermal infiltrate which is often accompanied by eosinophils, mast cells and plasma cells 131415161718. The cats body responds by producing antibodies which attack the healthy cells. Fusion podoplasty for the treatment of chronic fibrosing interdigital pyoderma in the dog. Pillow foot is associated with immune reaction when the plasma cells produce high amounts of antibodies that they start to attack the cats healthy cells, in this case it happens in the cats paw pads. We would rate this 10 stars if we could. Generally, all four feet are affected, but occasionally a cat will have only one affected foot. Other Scientific, Written by However, the exact relationship between FIV and feline plasma cell pododermatitis still remains unknown. Using holistic care for autoimmune conditions can greatly reduce the need to give your cat medications and better regulate their immune system. This is an uncommon disease affecting mostly older cats, with a mean age of 12 years (range 4-20 years)20 24. The disease can spread to the entire body and cause one or both of the front (metacarpal) and rear (metatarsal) pads to be damaged. Autoimmune diseases can be managed holistically by feeding your pet a low carbohydrate, anti-inflammatory diet and using supplements that help modulate the immune system. An ulcerated crusty pad in a cat with eosinophilic granuloma. A prescription of steroids may be useful in treating underlying immune disorders. Also Known As: Pillow foot Transmission or Cause: Plasma cell pododermatitis is an immune mediated disorder which causes soft swelling, deformation and sometimes ulceration of the paw pads. Update my browser now, David Grant continues the series of dermatology briefs. The cause of FPP is unknown, but The cause of FPP remains unknown, although the fact that immune cells are involved suggests some sort of overstimulation of the immune system. Treatment of Plasma Cell Pododermatitis in Cats Treatment options vary depending on the individual cats clinical signs or symptoms. Read more, Issue number 31.1 Doxycycline is one antibiotic that has properties that seem to regulate the immune system. Feline plasmacytic pododermatitis is an uncommon disease affecting either the metacarpal or metatarsal footpads. At my age do cats or dogs first experience plasma cell podo dermatitis? Posted on 2022-04-22 by . Toby has always bathed nervously to the point where he had furless patches & he has always been a small cat who weighs next to nothing. A detailed article from Old Maid Cat Lady; Pillow Foot - A summary from Mar Vista Animal Medical Center, and excellent source of veterinary information; Dietary therapy - Plasma cell pododermatitis resolution after dental and dietary therapy in two cats. What is feline plasma cell pododermatitis?Plasma cell pododermatitis (a mouthful, I know) is an inflammatory disease that affects the footpads of cats. Need Help? This can cause splitting, cracking, and irritation, no fun for a . This feline skin disease is treatable with surgical resection of the tumor. Courtesy of Dr. Federico Leone, Figure 4. In one retrospective study, 88% of carcinomas in the digits represented metastases from primary lung carcinoma 23. Eosinophilic granuloma is a cutaneous reaction pattern and rarely a final diagnosis. Clinical signs associated with the primary lung tumor are often absent. To use Epsom salt to treat pillow foot, we can soak the cats paw in the Epsom salt solution for around 10 minutes daily. Feline lung-digit syndrome (FLDS) describes an unusual pattern of metastasis from primary lung tumors, most commonly adenocarcinoma, to one or more digits20 2122. Rarely a single footpad will be affected. A dose of 7mg/kg once daily is given until improvement is noted within 2 to 6 weeks. Thrift E, Greenwell C, Turner AL, et al. A retrospective study of canine food hypersensitivity was performed through the examination of clinical records of suspected dogs examined at the Servio de . The exact cause of PCP has not been proven, but it is thought to be an overreaction of the immune system. Since the onset of the attacks are often associated with triggers such as stress, exposure to vaccines, environmental chemicals, or food allergens, its important to provide your cat with immune system support. Product CODE AN227 Pemphigus foliaceus (pages 1 -16) Equine Hoof Rot (or in other farm animals), Feline Plasma Cell Pododermatitis (foot rot, pillow foot in cats). Scott DW, Miller WH, Erb HN. This image is from a captive tiger (Panthera tigris) with suspected PCP; note the ulceration which affects most of the pads but particularly the central metacarpal pad. Banovic F. Immune-Mediated Diseases. Histopathology features consist of nodular to diffuse granulomatous dermatitis with a prominent eosinophilic infiltrate and multi-focal areas of collagen surrounded by degranulated eosinophils, known as flame figures910 11. All four pads can be affected at the same time and in fact it is rare that only one of the legs becomes inflamed. Should I use special cat litter while his foot is affected. We were nervous to start the Power Probiotic as it is a little pricey with a no refund policy but we owed it to Toby to at least give it a try. Some pads may ulcerate, particularly in those cats with access to the outdoors and this will result in lameness, prompting veterinary advice. Rare skin disease of cats; rarer in dogs. Issue number 31.1 After just one week, we were able to notice a marked improvement in his mobility. The median age of onset is 6 years of age, with a range of 0.25-16 years 131415161718. His front paws would swell and bleed and looked so painful. But it may cause brain damage if ingested by new born kittens. Sugiyama H, Maruo T, Shida T, et al. It may take up several months for the cat to recover. Previous publications reported concurrent FIV infection in 44-62% of cases, but the association is possibly incidental rather than causal45 67 8. Now comes the wonderful ending to this story, just last November 2017 Frederick returned home! These 14 specimens came from a previous prospective study. Stage 1: The paw pad may be slightly puffy and tender. We have been unable to get him to the vet's office because of COVID, and most recently because they are only seeing patients in the parking lot! Thats why it is important to treat the pillow paw as soon as possible to prevent for more serious issue. Doxycycline at 10mg/kg has been used extensively in plasma cell pododermatitis and improvement should be seen within one to two months. It usually affects more than one paws and rarely affect just one paw. Definitive diagnosis is based on histopathology, but should avoid sampling ulcerated lesions. Various treatments have been described for feline plasma cell pododermatitis. Pododermatitis is often paired with renal amyloidosis (a kidney disease) or plasma cell stomatitis (a disease of the mouth). Within 4 weeks, Tobys paws had completely healed & the swelling was gone and it has stayed that way.

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